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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1018095Generated: October 30, 2026

Ethanol → Ethyl 2-[4-(cyclopropanecarbonyl)phenyl]-2-methylpropanoate

https://huagongshe.com/reaction/1018095

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactant2-(4-Cyclopropanecarbonyl-phenyl)-2-methylpropionamideHCID 23499851—
ProductEthyl 2-[4-(cyclopropanecarbonyl)phenyl]-2-methylpropanoateHCID 9813859—

Reaction Steps

Dissolve 2-(4-cyclopropanecarbonyl-phenyl)-2-methyl-propionamide (100 mg) in ethanol and bubble in hydrochloride gas for 5 minutes while stirring. Reflux for 10 hours, distill off the ethanol and extract into ethyl acetate. Evaporate the solvent in vacuo to give the title compound as an oil (50 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06479663B2
Source datasetuspto-grants-2002_11
ORD IDord-feae2e7fc27b4da5bfff4221c5862326
Source noteuspto-grants-2002_11