HCID 22954341, compound → HCID 69830701, compound

HRID 1018154Notes

Reaction equation

HRID 1018154 reaction equation
[CH2:1](OC(C1(CCCCSC)CCC1)=O)[CH3:2].[CH2:16]([O:18][C:19]([C:21]1([CH2:25][CH2:26][CH2:27][CH2:28][S:29]([CH3:32])(=[O:31])=[O:30])[CH2:24][CH2:23][CH2:22]1)=[O:20])[CH3:17]>>[CH2:16]([O:18][C:19]([C:21]1([CH2:25][CH2:26][CH2:27][CH2:28][S:29]([CH3:32])(=[O:30])=[O:31])[CH2:24][CH2:23][CH:22]1[CH2:1][CH3:2])=[O:20])[CH3:17]

Participants

3

Reactant 2

HCID 22954341HCID 22954341, compoundHCID 22954342HCID 22954342, compound

Product 1

HCID 69830701HCID 69830701, compoundYield 92%

Procedure

Using the general procedure described in example 46, starting with 1-[4-(methylthio)butyl]cyclobutanecarboxylic acid ethyl ester, 1-[4-(methylsulfonyl)-butyl]cyclobutanecarboxylic acid ethyl ester was prepared in 92% yield as a colorless oil. HR MS: Obs. mass, 262.1231. Calcd. mass, 262.1238, M+.

Workup

  1. customwas prepared in 92% yield as a colorless oil

Sources & evidence

ORD record
ord-79d5796b60834938accb1b65fd015f45
Source dataset
uspto-grants-2002_11
Patent number
US06479666B2

Reaction notes

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