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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1018281Generated: October 30, 2026

2-Morpholinoethylamine → 1-cyclohexyl-2-(3-furyl)-N-[(1S)-1-[(5-hydroxy-1H-indol-3-yl)methyl]-2-(2-morpholinoethylamino)-2-oxo-ethyl]benzimidazole-5-carboxamide

https://huagongshe.com/reaction/1018281

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MorpholinoethylamineHCID 408285—
ReactantHCID 491192HCID 491192—
Product1-cyclohexyl-2-(3-furyl)-N-[(1S)-1-[(5-hydroxy-1H-indol-3-yl)methyl]-2-(2-morpholinoethylamino)-2-oxo-ethyl]benzimidazole-5-carboxamideHCID 491194—

Reaction Steps

The carboxylic acid of example 133 was coupled to aminoethylmorpholine under standard TBTU conditions to yield the title compound of example 135.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06479508B1
Source datasetuspto-grants-2002_11
ORD IDord-ac62a7fa9b094beaa945f7cf17e3ef69
Source noteuspto-grants-2002_11