反应详情

The title compound was prepared according to the procedure of Example 20, with the modification that benzaldehyde was used in step b instead of 2-naphthaldehyde and 3-amino-benzoic acid benzyl ester was used in step d instead of 5-amino-isophthalic acid dibenzyl ester. 1H NMR (300 MHz, d6-DMSO) 13.00 (1H, br s), 9.86 (1H, s), 8.51 (1H, s), 8.07 (2H, d), 7.99 (1H, d), 7.63 (1H, d), 7.42 (4H, m), 2.94 (2H, d), 1.98 (1H, m), 1.66-1.22 (12H, m). The acid was converted to the N-methyl-D-glucamine salt and lyophilised from water/dioxan. Found: C, 59.97; H, 7.32; N, 8.72%; C32H44N4O8.1.5 H2O requires: C, 60.04; H, 7.41; N, 8.75%.