Benzyloxycarbonylglycine → HCID 57311714, compound

Participants

Reaction Steps

3-Amino-benzoic acid methyl ester hydrochloride (1.88 g, 10.0 mmol) was reacted with N-α-CBZ-glycine (3.14 g, 15.0 mmol) according to the procedure of Example 102, step a to afford the product (3.12 g, 91%). 1H NMR (300MHZ, CDCl3) 10.18 (1H, br s), 8.26 (1H, m), 7.84 (1H, d), 7.65 (1H, d), 7.55 (1H, d), 7.48-7.22 (7H, m), 5.05 (2H, s), 3.85 (3H, s), 3.83 (2H, d).

Provenance & Evidence