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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1018346Generated: October 26, 2026

Tosylmethyl isocyanide → 1,7,7-Trimethyl-bicyclo[2.2.1]heptane-2-carbonitrile

https://huagongshe.com/reaction/1018346

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTosylmethyl isocyanideHCID 161915—
ReactantHCID 9543187HCID 9543187—
Product1,7,7-Trimethyl-bicyclo[2.2.1]heptane-2-carbonitrileHCID 18405550—

Reaction Steps

(1R)-(+)-Camphor was converted to the nitrile using tosylmethyl isocyanide according to the procedure of O. H. Oldenziel (O. H. Oldenziel, D. van Leusen, and A. M. van Leusen J.Org.Chem. 1977, 42, 3114).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06479531B1
Source datasetuspto-grants-2002_11
ORD IDord-ab03afc53d47427c8a72abb2a6f741a2
Source noteuspto-grants-2002_11