HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylamine → 5-Diethylamino-Furan-2-Carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | 5-Bromofuran-2-carbaldehyde | HCID 600328 | — |
| Catalyst | Trioctylmethylammonium chloride | HCID 21218 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 5-Diethylamino-Furan-2-Carbaldehyde | HCID 768638 | 85% |
Reaction Steps
5-Bromofuraldehyde was dissolved in dimethylsulfoxide (DMSO) and 1-2 drops of Aliquart 336 (tricaprylylmethylammonium chloride, produced by Aldrich Co.) was added to the solution. 10 Equivalents diethylamine was added to the mixture and refluxed for 4 days. The remaining diethylamine was removed from the reaction mixture and subjected to extraction and column chromatography to obtain 5-diethylamino-2-furaldehyde with a yield of 85%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06482494B2 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-abe686e4d26d4970b2b8826f02866b32 |
| Source note | uspto-grants-2002_11 |