Sodium Hydroxide → L-Leucine

HRID 1018409Notes

Reaction equation

HRID 1018409 reaction equation
Cl.[NH2:2][C@H:3]([C:8]([OH:10])=[O:9])[CH2:4][CH:5]([CH3:7])[CH3:6].[OH-].[Na+]>O>[NH2:2][C@H:3]([C:8]([OH:10])=[O:9])[CH2:4][CH:5]([CH3:7])[CH3:6]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 102479Leucine hydrochloride

Product 1

HCID 6106L-Leucine

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A similar dispersion was prepared with the use of PLURONIC F-68 as stabilizer. An amount of 0.152 grams of leucine hydrochloride was added to 0.852 grams of nanostructured reverse bicontinuous cubic phase material as above, and an upper phase consisting of 0.08 grams of F-68, 1.0 gram of 1M sodium hydroxide, and 3.0 grams of water was overlaid on the nanostructured reverse bicontinuous cubic phase material and sonicated. Again, a milky-white dispersion of leucine-coated microparticles was formed, where this time the F-68 amphiphilic block copolymer surfactant coated the outer (leucine-based) surface of the particles.

Workup

  1. customsonicated

Sources & evidence

ORD record
ord-803c8fbd0ebe4050910e93615484cb8d
Source dataset
uspto-grants-2002_11
Patent number
US06482517B1

Reaction notes

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