Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Thiopheneacetic acid → Acetamidomethyl thiolacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Thiopheneacetic acid | HCID 15970 | — |
| 반응물 | Formicin | HCID 69365 | — |
| 생성물 | Acetamidomethyl thiolacetate | HCID 57065091 | 64% |
반응 단계
N-(Hydroxymethyl)-acetamide (13.4 g, 0.15 mol) and thiolacetic acid (14.3 g, 0.188 mol) were heated for 3 days at 40° C. The resulting mixture was chromatographed on silica gel (63-200 um, 700 g) with toluene-ethyl acetate 4:1 and 1:1 to give pure crystalline acetamidomethyl thiolacetate (14.2 g, 64%), m.p. 93-94° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06482818B2 |
| 출처 데이터셋 | uspto-grants-2002_11 |
| ORD ID | ord-6423c437545145188cc82f99b0435964 |
| 출처 메모 | uspto-grants-2002_11 |