HCID 54456843, compound → 1-(4-Ethoxyphenyl)-2-methyl-1-penten-3-ol

Participants

Reaction Steps

To a solution of 3-(4-ethoxyphenyl)-2-methylpropenaldehyde (10 g, 0.053 mol) in dried diethyl ether (150 ml) cooled to −15° C. and stirred under an atmosphere of nitrogen was added a solution of ethylmagnesium bromide in diethylether (3M, 19.3 ml) The reaction mixture was allowed to warm to room temperature and after ½ h poured onto ice cold aqueous hydrochloric acid (2M, 50 ml) and the organic phase washed with water and brine. The organic phase was dried over magnesium sulphate, filtered and evaporated to give 1-(4-ethoxyphenyl)-3-hydroxy-2-methylpent-1-ene as a colourless oil.

Provenance & Evidence