HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylene Glycol → HCID 13214222, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylene Glycol | HCID 174 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 2-Methylbenzenesulfonic acid | HCID 6925 | — |
| Reactant | 3-Methyl-2-cyclohexen-1-one | HCID 14511 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 13214222 | HCID 13214222 | 62% |
Reaction Steps
A mixture of 3-methyl-2-cyclohexenone (4 g, 36.36 mmol), toluenesulfonic acid (100 mg) and ethylene glycol (7 mL) in 100 mL of toluene is refluxed overnight and water formed is removed by Dean-Stark trap. The residue after concentration is chromatographed on silica gel (10% ethyl acetate/hexane) to give 3.36 g (62%) of 7-methyl-1,4-dioxa-spiro[4.5]dec-7-ene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06482834B2 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-79842ae9c2fd48b29dc5761ff31c4ee3 |
| Source note | uspto-grants-2002_11 |