HCID 15541833, compound → HCID 9803157, compound

Participants

Reaction Steps

To a suspension of 82 g (0.068 mol) of pyridinium chlorochromate on alumina in 230 ml of CH2Cl2, 10 g (0.023 mol) of 4-(2,3-dichlorophenyl)-2,6-dimethyl 1,4-dihydropyridine-3,5-dicarboxylic acid 3-methyl ester 5-(tetrahydrofuran-2-ylmethyl) ester were added, and the mixture was maintained with strong stirring during 7 hours. The insoluble solid was filtered and the remaining liquid was washed with water (3×250 ml), dried with anh. Na2SO4 and concentrated at low pressure. Finally, the product was obtained as an oil, with a yield of 87%.

Provenance & Evidence