HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl acetoacetate → HCID 4448724, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl acetoacetate | HCID 7757 | — |
| Reactant | o-(Trifluoromethyl)benzaldehyde | HCID 123067 | — |
| Reactant | HCID 69946325 | HCID 69946325 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 4448724 | HCID 4448724 | — |
Reaction Steps
A solution of 90 ml (118.8 g; 0.68 mol) of 2-trifluoromethyibenzaldehyde, 75 ml (79.23 g; 0.68 mol) of methyl acetoacetate and 126.38 g (0.68 mol) of (tetrahydrofuran-2-ylmethyl)-3-aminocrotonate in 700 ml of 2-propanol, was refluxed in the absence of light along 10 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06482841B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-a04158571dbd44ee837d86ace4e30e4c |
| Source note | uspto-grants-2002_11 |