Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | HCID 54335594 | HCID 54335594 | — |
| Reactant | HCID 69946325 | HCID 69946325 | — |
| Product | HCID 69946164 | HCID 69946164 | 80% |
Reaction Steps
A solution of 15 g (0.05 mol) of tetrahydrofuran-2-ylmethyl 3-nitrobenzylidenacetoacetate and 8.7 g (0.05 mol) of (tetrahydrofuran-2-ylmethyl)-3-aminocrotonate in 50 ml of abs ethanol, was refluxed with stirring, in the absence of light, along 8 hours. The reaction mixture was then cooled to −10° C. A yellow soild (mp 122-3° C., EtAcO) was obtained with a yield of 80%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06482841B1 |
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| Source dataset | uspto-grants-2002_11 |
|---|
| ORD ID | ord-8360499970ab41c5b6bdc33e2fad5369 |
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| Source note | uspto-grants-2002_11 |
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