HCID 69946086, compound → HCID 22898674, compound

Participants

Reaction Steps

A mixture of 11 g (0,025 mol) of 2,6-dimethyl-4-(2,3-dimethoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-methyl ester 5-(tetrahydrofuran-2-ylmethyl) ester and 92 g (0,076 mol) of pyridinium chlorochromate absorbed on alumina, was suspended on 250 ml of CH2C12, and the whole mixture was maintained on stirring at room temperature for 6 hours. The remaining solid was eliminated by filtration, and the liquid was washed with water (3×300 ml), dried over anh. Na2SO4, and concentrated at reduced pressure, to dryness. The product was obtained as an oil, which was purified by column chromatography (Silicagel, n-hexane:EtAcO, 8:2) with a yield of 79%.

Provenance & Evidence