1-Phenyl-1,3,8-triazaspiro(4.5)decan-4-one → HCID 18401658, compound

HRID 1018548Notes

Reaction equation

HRID 1018548 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:10]=1)[C:5](Cl)=[O:6].[C:15]1([N:21]2[C:25]3([CH2:30][CH2:29][NH:28][CH2:27][CH2:26]3)[C:24](=[O:31])[NH:23][CH2:22]2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:10]=1)[C:5]([N:28]1[CH2:27][CH2:26][C:25]2([N:21]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH2:22][NH:23][C:24]2=[O:31])[CH2:30][CH2:29]1)=[O:6]

Participants

3

Reactant 2

HCID 705561-Phenyl-1,3,8-triazaspiro(4.5)decan-4-oneHCID 5193643-Fluoro-5-(trifluoromethyl)benzoyl chloride

Product 1

HCID 18401658HCID 18401658, compound

Procedure

The title compound, MS: m/e=422.3 (M+H+), was prepared in accordance with the general method of example 1 from 3-fluoro-5-(trifluoromethyl)benzoyl chloride and 1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one.

Sources & evidence

ORD record
ord-7910ecd13a0e4969a1ef3660c298ee00
Source dataset
uspto-grants-2002_11
Patent number
US06482829B2

Reaction notes

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