Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1018557Generated: October 25, 2026

2-Chloro-4,6-dimethoxypyrimidine → 8-(3,5-Bis-trifluoromethyl-benzoyl)-3-(4,6-dimethoxy-pyrimidin-2-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one

https://huagongshe.com/reaction/1018557

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4,6-dimethoxypyrimidineHCID 5152323—
ReactantHCID 18401725HCID 18401725—
Product8-(3,5-Bis-trifluoromethyl-benzoyl)-3-(4,6-dimethoxy-pyrimidin-2-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-oneHCID 18401653—

Reaction Steps

The title compound, MS: m/e=610.0 (M+H+), was prepared in accordance with the general method of example 4 from 8-(3,5-bis-trifluoromethyl-benzoyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one and 2-chloro-4,6-dimethoxypyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06482829B2
Source datasetuspto-grants-2002_11
ORD IDord-bb6668d16c2241fab6dd02662c222549
Source noteuspto-grants-2002_11