HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 8-(3,5-Bis-trifluoromethyl-benzoyl)-3-(2-dimethylamino-ethyl)-1-o-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 8-(3,5-Bis-trifluoromethyl-benzoyl)-3-(2-hydroxy-ethyl)-1-o-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one | HCID 18401656 | — |
| Product | 8-(3,5-Bis-trifluoromethyl-benzoyl)-3-(2-dimethylamino-ethyl)-1-o-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one | HCID 18401629 | — |
Reaction Steps
The title compound, MS: m/e=557.2 (M+H+), was prepared in accordance with the general method of example 48 from 8-(3,5-bis-trifluoromethyl-benzoyl)-3-(2-hydroxy-ethyl)-1-o-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one and dimethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06482829B2 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-def3531f046646e4adcb032596c87ffb |
| Source note | uspto-grants-2002_11 |