HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → 8-(3,5-Bis-trifluoromethyl-benzoyl)-3-(2-pyrrolidin-1-yl-ethyl)-1-o-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 8-(3,5-Bis-trifluoromethyl-benzoyl)-3-(2-hydroxy-ethyl)-1-o-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one | HCID 18401656 | — |
| Product | 8-(3,5-Bis-trifluoromethyl-benzoyl)-3-(2-pyrrolidin-1-yl-ethyl)-1-o-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one | HCID 10121035 | — |
Reaction Steps
The title compound, MS: m/e=583.2 (M+H+), was prepared in accordance with the general method of example 48 from 8-(3,5-bis-trifluoromethyl-benzoyl)-3-(2-hydroxy-ethyl)-1-o-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one and pyrrolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06482829B2 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-3e12becccdc047c4af3c84e4406afd3c |
| Source note | uspto-grants-2002_11 |