Methyl iodide → HCID 18401641, compound

HRID 1018585Notes

Reaction equation

[CH2:1]([N:8]1[C:12]2([CH2:17][CH2:16][N:15]([C:18](=[O:33])[C:19]3[CH:24]=[C:23]([C:25]([F:28])([F:27])[F:26])[CH:22]=[C:21]([C:29]([F:32])([F:31])[F:30])[CH:20]=3)[CH2:14][CH2:13]2)[C:11](=[O:34])[NH:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:35]I>>[CH2:1]([N:8]1[C:12]2([CH2:17][CH2:16][N:15]([C:18](=[O:33])[C:19]3[CH:20]=[C:21]([C:29]([F:32])([F:31])[F:30])[CH:22]=[C:23]([C:25]([F:26])([F:27])[F:28])[CH:24]=3)[CH2:14][CH2:13]2)[C:11](=[O:34])[N:10]([CH3:35])[CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 18401636HCID 18401636, compound

Product 1

HCID 18401641HCID 18401641, compound

Procedure

The title compound, MS: m/e=500.3 (M+H+), was prepared in accordance with the general method of example 71 from 1-benzyl-8-(3,5-bis-trifluoromethyl-benzoyl)-1,3,8-triaza-spiro[4.5]decan-4-one and methyliodide.

Sources & evidence

ORD record: ord-1f92aa8d517c4f549124525df4989b5f
Source dataset: uspto-grants-2002_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06482829B2

Reaction notes

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