HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroethyl methyl ether → Rac-8-(3,5-bis-trifluoromethyl-benzoyl)-3-(2-methoxy-ethyl)-2-methyl-1-o-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroethyl methyl ether | HCID 12316 | — |
| Reactant | (Rac)-8-(3,5-bis-trifluoromethyl-benzoyl)-2-methyl-1-o-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one | HCID 10163903 | — |
| Product | Rac-8-(3,5-bis-trifluoromethyl-benzoyl)-3-(2-methoxy-ethyl)-2-methyl-1-o-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one | HCID 10209666 | — |
Reaction Steps
The title compound, MS: m/e=542.2 (M+H+), was prepared in accordance with the general method of example 99 from (rac)-8-(3,5-bis-trifluoromethyl-benzoyl)-2-methyl-1-o-tolyl-1,3,8-triaza-spiro[4.5]decan-4-one and 2-chloroethyl-methyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06482829B2 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-1ca06d0d577f420d9b7c954f9cdb42a0 |
| Source note | uspto-grants-2002_11 |