3-Chloro-N,N-dimethyl-1-propanamine → HCID 18401630, compound

HRID 1018620Notes

Reaction equation

HRID 1018620 reaction equation
[F:1][C:2]([F:34])([F:33])[C:3]1[CH:4]=[C:5]([CH:26]=[C:27]([C:29]([F:32])([F:31])[F:30])[CH:28]=1)[C:6]([N:8]1[CH2:25][CH2:24][C:11]2([N:15]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[CH3:22])[C:14](=[O:23])[NH:13][CH2:12]2)[CH2:10][CH2:9]1)=[O:7].[CH3:35][N:36]([CH3:41])[CH2:37][CH2:38][CH2:39]Cl>>[F:34][C:2]([F:1])([F:33])[C:3]1[CH:4]=[C:5]([CH:26]=[C:27]([C:29]([F:32])([F:31])[F:30])[CH:28]=1)[C:6]([N:8]1[CH2:25][CH2:24][C:11]2([N:15]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[CH3:22])[C:14](=[O:23])[N:13]([CH2:39][CH2:38][CH2:37][N:36]([CH3:41])[CH3:35])[CH2:12]2)[CH2:10][CH2:9]1)=[O:7]

Participants

3

Reactant 2

HCID 669603-Chloro-N,N-dimethyl-1-propanamineHCID 18401720HCID 18401720, compound

Product 1

HCID 18401630HCID 18401630, compound

Procedure

The title compound, MS: m/e=571.1 (M+H+), was prepared in accordance with the general method of example 99 from 8-(3,5-bis-trifluoromethyl-benzoyl)-1-o-tolyl-1,3,8-triaza-spiro[4.5]decan-2-one and 3-dimethylamino-1-propyl chloride.

Sources & evidence

ORD record
ord-5c74eef910774bc48a1910d04f793c00
Source dataset
uspto-grants-2002_11
Patent number
US06482829B2

Reaction notes

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