HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → HCID 178424862, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | HCID 10268158 | HCID 10268158 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | HCID 178424862 | HCID 178424862 | 90% |
Reaction Steps
Alternatively, (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1-(1-hydroxyethyl)-1,3-dihydro-2H-indol-2-one (4b) was prepared in >90% yield by treating 1-{(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)-methylidene]-2-oxo-2,3-dihydro-1H-indol-1-yl}ethyl acetate (4a) (500 mg) with aqueous acetonitrile (10 mL) and formic acid (200 mg) overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06482848B2 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-65c9fab07b1e4d6b9a3ac0bd52189ba2 |
| Source note | uspto-grants-2002_11 |