HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiosemicarbazide → N-[4-[(carbamothioylhydrazinylidene)methyl]-2-fluorophenyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiosemicarbazide | HCID 2723789 | — |
| Reactant | N-(2-Fluoro-4-formylphenyl)acetamide | HCID 10192606 | — |
| Product | N-[4-[(carbamothioylhydrazinylidene)methyl]-2-fluorophenyl]acetamide | HCID 3001792 | — |
Reaction Steps
The product was characterized as 4-acetamido-3-fluorobenzaldehyde 15. 4-Acetamido-3-fluorobenzaldehyde 15 reacts with thiosemicarbazide to yield 4-acetamido-3-fluorobenzaldehyde thiosemicarbazone 16. Compound 16 has been tested and shown to be both non-toxic and highly active against M. Tuberculosis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06482982B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-8c3a0941de484ebf8cc47aa28772feac |
| Source note | uspto-grants-2002_11 |