p-Toluenesulfonic acid → 1-(1,1-Dimethoxyethyl)-4-(4,4-dimethylcyclohex-1-enyl)benzene

Participants

Reaction Steps

36.13 g of 1-[4-(4,4-dimethylcyclohex-1-enyl)phenyl]ethanone (compound VI.1) in 250 ml of methanol are stirred for 12 hours at room temperature in the presence of 0.5 g of para-toluenesulphonic acid (PTSA) and 13 ml of trimethyl-ortho-formate. The solvents are partially evaporated off under reduced pressure. A 50% solution of potassium hydroxide in methanol is added and the solvents are then evaporated off under reduced pressure. The residue obtained is taken up in diisopropyl ether and the solvent is then evaporated off under reduced pressure.

Provenance & Evidence