2,5-Dibromopyridine → HCID 18398502, compound

HRID 1018883Notes

Reaction equation

HRID 1018883 reaction equation
BrC1C=CC(Br)=CN=1.[F:9][C:10]1[CH:18]=[C:17]([C:19]2[CH:24]=[CH:23][C:22](Br)=[CH:21][N:20]=2)[CH:16]=[C:15]2[C:11]=1[CH2:12][CH:13]([CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[CH2:14]2.[CH2:34]=[CH:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41].B1C2CCCC1CCC2>>[F:9][C:10]1[CH:18]=[C:17]([C:19]2[CH:24]=[CH:23][C:22]([CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH3:41])=[CH:21][N:20]=2)[CH:16]=[C:15]2[C:11]=1[CH2:12][CH:13]([CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[CH2:14]2

Participants

4

Reactant 3

HCID 693532,5-DibromopyridineHCID 69975883HCID 69975883, compoundHCID 178419116HCID 178419116, compound

Product 1

HCID 18398502HCID 18398502, compound

Procedure

Obtained by reacting with 2,5-dibromopyridine to form 4-fluoro-6-(5-bromo-pyridine-2-yl)-2-octyl indane and subsequent reaction with the octene-9-BBN-adduct.

Workup

  1. customObtained
  2. customto form

Sources & evidence

ORD record
ord-245958e9678b41d39deeaf374e41b87b
Source dataset
uspto-grants-2002_11
Patent number
US06485797B1

Reaction notes

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