Water → HCID 12052173, compound

Participants

Reaction Steps

1-Benzylthio-4-phenylphthalazine (98 mg; 0.3 mmol from Example 1B) in N,N-dimethylacetamide (13 ml) is cooled in an ice bath. Oxone® (2KHSO5.KHSO4.K2SO4) (670 mg; 1.1 mmol) is added, followed by the stepwise addition of water (1.4 ml). The mixture is stirred at room temperature for 2 days, is poured into ice water, is stirred 10 minutes and is filtered to give the title compound as a solid (53 mg) (R1=phenyl, R2=phenyl, A=benzene, Y1=CH2, m=0, n=1, p=0, q=2).

Provenance & Evidence