Hydrazine → HCID 178518901, compound

HRID 1018930Notes

Reaction equation

HRID 1018930 reaction equation
[NH2:1][NH2:2].Cl.[N:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10]([C:12]1[CH:20]=[CH:19][CH:18]=[CH:17][C:13]=1[C:14](O)=[O:15])=O>C(O)C>[OH:15][C:14]1[C:13]2[C:12](=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:10]([C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][N:4]=2)=[N:2][N:1]=1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 70156286HCID 70156286, compound

Product 1

HCID 178518901HCID 178518901, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A 3M-solution of hydrazine (20 ml, 60 mmol) in ethanol is added to the solution of crude 2-(2-pyridylcarbonyl)benzoic acid hydrochloride(4.54 g, 20 mmol), and the mixture is stirred at room temperature for 5 hours. Precipitation yields 1-hydroxy-4-(2-pyridyl)phthalazine.

Workup

  1. customPrecipitation

Sources & evidence

ORD record
ord-332e4dfa61344752b4adb8c97ba514d9
Source dataset
uspto-grants-2002_11
Patent number
US06486158B1

Reaction notes

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