Hydrazine → HCID 18399544, compound

HRID 1018931Notes

Reaction equation

HRID 1018931 reaction equation
[NH2:1][NH2:2].[C:3]([C:11]1[C:16]([C:17]([OH:19])=O)=[CH:15][CH:14]=[CH:13][N:12]=1)(=O)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1>>[C:4]1([C:3]2[C:11]3[C:16](=[CH:15][CH:14]=[CH:13][N:12]=3)[CH:17]([OH:19])[NH:2][N:1]=2)[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

3

Reactant 2

HCID 9321HydrazineHCID 8245992-benzoylnicotinic acid

Product 1

HCID 18399544HCID 18399544, compound

Procedure

A 3M ethanolic solution of hydrazine (20 ml, 60 mmol) is added to an ethanolic solution of 2-benzoyl-3-pyridine carboxylic acid (Aldrich product) (4.54 g, 20 mmol), and the mixture is stirred at room temperature for 24 hours. Precipitation yields 4-Phenyl-1,2-dihydro-5-azaphthalazin-1-ol.

Workup

  1. customPrecipitation

Sources & evidence

ORD record
ord-95e3bd5f04534379a1aff2ed58dc2121
Source dataset
uspto-grants-2002_11
Patent number
US06486158B1

Reaction notes

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