Water → HCID 18398677, compound

Participants

Reaction Steps

To a solution of POBr3 (150 mg, 0.39 mmol) in CH2Cl2 (4 mL) and DMF (2 mL) was added the product of step 2 (150 mg, 0.39 mmol). The mixture was stirred at r.t. for 0.5 h. H2O was added and the mixture was extracted with EtOAc. The combined organic extracts were washed with brine, dried (anhyd. MgSO4) and concentrated in vacuo. The residue was purified by chromatography on silica gel to give 159 mg (91%) of the title compound.

Provenance & Evidence