HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1019015Generated: October 31, 2026
Diethyl aluminum cyanide → HCID 57254707, compound
https://huagongshe.com/reaction/1019015
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl aluminum cyanide | HCID 16686413 | — |
| Reactant | HCID 57263809 | HCID 57263809 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57254707 | HCID 57254707 | 26.7% |
Reaction Steps
8α,9α-Epoxycholest-5-en-3βol (200mg) is dissolved in dichloromethane and the solution is cooled to 0° C. 1.5 ml of a diethylaluminumcyanide-solution (1 M in toluene) is added dropwise. After addition, the reaction mixture is warmed to room temperature and stirred for additional 18 hours. After basic work-up and column chromatography, cholesta-5,8,14-triene-3βol (51 mg) is isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06486145B2 |
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| Source dataset | uspto-grants-2002_11 |
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| ORD ID | ord-aceef35d7a8046528e7993b0ab1281d2 |
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| Source note | uspto-grants-2002_11 |
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