HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium → HCID 20739691, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium | HCID 3028194 | — |
| Reactant | HCID 57263809 | HCID 57263809 | — |
| Solvent | Diethylamine | HCID 8021 | — |
| Product | HCID 20739691 | HCID 20739691 | 30.8% |
Reaction Steps
8α,9α-Epoxycholest-5-en-3β-ol(200 mg) is dissolved in 13 ml diethylamine at −20° C. Lithium (100 mg) is added in small portions. The reaction mixture is stirred for 3 hours. After aqueous work-up, a crude product (207 mg) is isolated. Crystallization from diisopropylether yields cholest-5-ene-3β,9α-diol (62 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06486145B2 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-6fb0d75408044b0ca1f5708aed47d327 |
| Source note | uspto-grants-2002_11 |