HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-[3-(imidazol-1-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoate → Methyl 5-[3-(imidazol-1-yl)prop-1-en-1-yl]-2-(4-fluorophenethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-[3-(imidazol-1-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoate | HCID 54479740 | — |
| Reactant | 4-(4-Fluorophenethyl)-3-methoxycarbonylbenzyl triphenylphosphonium bromide | HCID 86590341 | — |
| Product | Methyl 5-[3-(imidazol-1-yl)prop-1-en-1-yl]-2-(4-fluorophenethyl)benzoate | HCID 53807049 | 70% |
Reaction Steps
Methyl 5-[3-(imidazol-1-yl)prop-1-en-1-yl]-2-(4-fluorophenethyl)benzoate was prepared in a similar way to that described for methyl 4-[3-(imidazol-1-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoate in Example 2 but using 4-(4-fluorophenethyl)-3-methoxycarbonylbenzyl triphenylphosphonium bromide instead of 3-(4-fluorophenyl)4-methoxycarbonylbenzyl triphenylphosphonium bromide. Yield: 70%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06486156B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-1ab68eb744bf485985a067d58a11ec9e |
| Source note | uspto-grants-2002_11 |