HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzylimidazole → Methyl 4-[3-(1-benzylimidazol-2-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzylimidazole | HCID 77918 | — |
| Reactant | Methyl 2-(4-fluorophenyl)-4-(3-bromoprop-1-en-1-yl)benzoate | HCID 54112501 | — |
| Reactant | Methyl 4-[3-(1-methylimidazol-2-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoate | HCID 54337160 | — |
| Product | Methyl 4-[3-(1-benzylimidazol-2-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoate | HCID 53719705 | 76% |
Reaction Steps
Methyl 4-[3-(1-benzylimidazol-2-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoate was prepared from methyl 4-(3-bromoprop-1-en-1-yl)-2-(4-fluorophenyl)benzoate as described for methyl 4-[3-(1-methylimidazol-2-yl)prop-1-en-1-yl]-2-(4-fluorophenyl)benzoate in Example 19, but using N-benzylimidazole. Yield: 76%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06486156B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-41fa4c3f6369430aac42831f301170f5 |
| Source note | uspto-grants-2002_11 |