Formaldehyde → HCID 18400136, compound

HRID 1019083Notes

Reaction equation

HRID 1019083 reaction equation
[N+:1]([C:4]1[C:10]([CH2:11][CH3:12])=[C:9]([N+:13]([O-:15])=[O:14])[CH:8]=[C:7]([CH3:16])[C:5]=1[NH2:6])([O-:3])=[O:2].[CH2:17]=O>S(=O)(=O)(O)O>[CH3:17][NH:6][C:5]1[C:7]([CH3:16])=[CH:8][C:9]([N+:13]([O-:15])=[O:14])=[C:10]([CH2:11][CH3:12])[C:4]=1[N+:1]([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 12051205HCID 12051205, compound

Product 1

HCID 18400136HCID 18400136, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

This compound is made according to Scheme 1. 2,4-Dinitro-3-ethyl-6-methylaniline is treated with paraformaldehyde in concentrated sulfuric acid to afford N-methyl-2,4-dinitro-3-ethyl-6-methylaniline. The synthesis is completed in the same manner as 4-ethyl-5-(2-imidazolinylamino)benzimidazole (see Example 2).

Sources & evidence

ORD record
ord-326dc5d78b564e939009eeac102684ee
Source dataset
uspto-grants-2002_11
Patent number
US06486190B1

Reaction notes

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