HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → 3-iodo-4-(4-(methylthio)phenyl)-2-(5H)-furanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | 4-(4-(methylthio)phenyl)-2-(5H)-furanone | HCID 12150589 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 3-iodo-4-(4-(methylthio)phenyl)-2-(5H)-furanone | HCID 12150590 | — |
Reaction Steps
To a solution of 3 g of the product of Step 2 in 30 ml of pyridine is added 8.7 g of I2. The mixture is stirred for 24 h and then diluted with 200 ml of ether, washed with 100 ml of 5N HCl and 50 ml of 5N Na2S2O3. The ether layer is dried over Na2SO4 and concentrated to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06486194B2 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-2f3a64a60356462a9692643ee03cbf07 |
| Source note | uspto-grants-2002_11 |