反应详情

温度

25 °C

A 33.18 g (0.090 mol) portion of N-octadecanoyl-N′,N′-dimethyl-1,3-diaminopropane and 120 ml of chloroform were put into a flask, and 22.44 g (0.099 mol) of 3-methyl-4-isopropylphenyl chloroacetate was added thereto at 25° C. spending 5 minutes. The reaction mixture was stirred at 25° C. for 36 hours and then, after confirming disappearance of the most part of chloroacetate by 1H-NMR, the solvent was evaporated under a reduced pressure. The thus obtained viscous oil was dissolved in 300 ml of acetone and cooled to 5 to 10° C. to effect precipitation of a white precipitate. Thereafter, in the same manner as described in Inventive Example 1, the title compound (to be referred to as betaine ester (12) hereinafter) was obtained as a white solid. Yield 41.80 g (0.070 mol; yield 78.0%).

1. customwas evaporated under a reduced pressure
2. dissolutionThe thus obtained viscous oil was dissolved in 300 ml of acetone
3. temperaturecooled to 5 to 10° C.
4. customprecipitation of a white precipitate