HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxy-5-nitro-2-(pyrrolidin-1-yl)pyridine → 4-Methoxy-2-(pyrrolidin-1-yl)-5-aminopyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxy-5-nitro-2-(pyrrolidin-1-yl)pyridine | HCID 57431518 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 4-Methoxy-2-(pyrrolidin-1-yl)-5-aminopyridine | HCID 57431519 | 96.3% |
Reaction Steps
The method described in Stage 12.2 is followed, starting from 1.5 g (6.72 mmol) of 4-methoxy-5-nitro-2-(pyrrolidin-1-yl)-pyridine, obtained in Stage 6.1, and 0.15 g of palladium on charcoal at 10%. We thus obtain 1.25 g of the expected product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08716273B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-2e71675bb5244e4896652bfab9997d2b |
| Source note | uspto-grants-2014_05 |