HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58256124, compound → HCID 59302552, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58256124 | HCID 58256124 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 59302552 | HCID 59302552 | 73.7% |
Reaction Steps
The product of step (e) (1.3 g, 3.39 mmol) was dissolved in 1:1 HOAc:water (40 mL), treated with Zn dust (0.44 g, 6.79 mmol), and heated to reflux for 1 hour. The reaction was cooled, diluted with water and extracted 2×EtOAc. The organic extracts were dried over MgSO4 and concentrated to give 0.76 g of the sub-title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08716276B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-6c1356435264465bbfaf0326249560e4 |
| Source note | uspto-grants-2014_05 |