HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59302552, compound → HCID 66934111, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59302552 | HCID 59302552 | — |
| Reactant | HCID 178477796 | HCID 178477796 | — |
| Catalyst | Bis(cyclopenta-1,4-dien-1-yl(diphenyl)phosphane);dichloropalladium;iron(2+) | HCID 178418228 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 66934111 | HCID 66934111 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
The product of step (f) (375 mg, 1.23 mmol) was dissolved in 4 mL dioxane and treated with Me2Zn (1.25 mL of 2M in toluene) and Pd(dppf)2Cl2. After heating to 100° C. for 3 h, the reaction was cooled, quenched with water, filtered through silica gel (washing with EtOAc), and concentrated to give 337 mg of the sub-title compound as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08716276B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-a27303f4584944f6b9e9009f43cf155a |
| Source note | uspto-grants-2014_05 |