Hydroxylamine → HCID 56932906, compound

Participants

Reaction Steps

The title compound was prepared in two steps according to Scheme 6 by (1) treating amine VII with n-butylsulfonyl chloride and TEA in dichloromethane, and (2) treating the ester intermediate with aqueous HONH2 and KOH. MS: calc'd (MH+) 327, exp (MH+) 327.4. 1H NMR (CD3OD, 400 MHz), 7.50 (d, 1H, J=7.6 Hz), 7.49 (s, 1H), 7.19 (d, 1H, J=8.0 Hz), 3.68 (m, 1H), 3.14 (m, 3H), 2.79-3.00 (m, 3H), 2.16 (m, 1H), 1.82 (m, 3H), 1.50 (m, 2H), 0.99 (m, 3H).

Provenance & Evidence