HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Azide → 2-[4-(2-Azidoethyl)-1-piperidinyl]-6-chloroquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | HCID 21096927 | HCID 21096927 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-[4-(2-Azidoethyl)-1-piperidinyl]-6-chloroquinoline | HCID 86661339 | — |
Reaction Steps
A solution of 5 g (13.55 mmol) of 2-[1-(6-chloroquinolin-2-yl)piperidin-4-yl]ethyl methanesulfonate, prepared in step 6.1., and 1.76 g (27.11 mmol) of sodium azide in 30 mL of N,N-dimethylformamide is refluxed for 4 hours, under an inert atmosphere.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08716289B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-0758aecb2e2c428ea618d0ce6aa09077 |
| Source note | uspto-grants-2014_05 |