Diisopropyl Ether → HCID 46901484, compound

Participants

Reaction Steps

The process is performed according to the method described in Example 1 (step 1.5.). Starting with 5.00 g (17.25 mmol) of 2-[1-(6-chloroquinolin-2-yl)piperidin-4-yl]ethylamine, prepared in step 6.3., 3.825 g (18.98 mmol) of 4-nitrophenyl chloroformate, 4.46 g (34.51 mmol) of N,N-diisopropylethylamine and 0.105 p (0.86 mmol) of N,N-dimethylaminopyridine, and after triturating from a mixture of diisopropyl ether and hexane, 7.8 g of pure product are obtained in the form of a white powder.

Provenance & Evidence