HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → N-(4-chlorophenyl)benzene-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | N-(4-chlorophenyl)-2-nitroaniline | HCID 89958 | — |
| Catalyst | Zinc | HCID 23994 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(4-chlorophenyl)benzene-1,2-diamine | HCID 522323 | — |
Reaction Steps
To a solution of 2-(4-chloroanilino)-nitrobenzene (57.0 g) in CH2Cl2 (40 mL) was added AcOH (90 mL), then Zn (105 g) was added in small portions. After Zn was added, the color of the mixture became light green, filtered by suction, washed with CH2Cl2. The filtrate was concentrated to dryness. Water was added, filtered, and washed with water to give a brown solid. This solid was used directly in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08716292B2 |
| Source dataset | uspto-grants-2014_05 |
| ORD ID | ord-35cadc19f4f94df7a24c21739d686c0d |
| Source note | uspto-grants-2014_05 |