Ethanol → 6-Methoxy-1-methyl-7-[[(2-phenyl-6-propylpiperidin-3-yl)amino]methyl]-3,4-dihydro-1,5-naphthyridin-2-one

HRID 101985Notes

Reaction equation

HRID 101985 reaction equation
[CH2:17]([CH3:18])[CH:19]1[CH2:20][CH2:21][CH:22]([NH:31][CH2:32][c:33]2[c:34]([O:45][CH3:46])[n:35][c:36]3[c:41]([cH:42]2)[N:40]([CH3:43])[C:39](=[O:44])[CH2:38][CH2:37]3)[CH:23]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[NH:24]1.[CH2:47]([OH:48])[CH3:49].[CH3:1][O:2][c:3]1[c:4]([CH:5]=[O:6])[cH:7][c:8]2[c:15]([n:16]1)[CH2:14][CH2:13][C:11](=[O:12])[N:9]2[CH3:10].[CH3:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH3:56]>>[CH3:1][CH2:18][CH2:17][CH:19]1[CH2:20][CH2:21][CH:22]([NH:31][CH2:32][c:33]2[c:34]([O:45][CH3:46])[n:35][c:36]3[c:41]([cH:42]2)[N:40]([CH3:43])[C:39](=[O:44])[CH2:38][CH2:37]3)[CH:23]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[NH:24]1

Participants

5

Reactant 4

HCID 702EthanolHCID 8900HeptaneHCID 219317147-[(6-ethyl-2-phenyl-piperidin-3-ylamino)-methyl]-6-methoxy-1-methyl-3,4-dihydro-1H-[1,5]naphthyridin-2-oneHCID 219317642-Methoxy-5-methyl-6-oxo-5,6,7,8-tetrahydro-[1,5]naphthyridine-3-carbaldehyde

Product 1

HCID 219318346-Methoxy-1-methyl-7-[[(2-phenyl-6-propylpiperidin-3-yl)amino]methyl]-3,4-dihydro-1,5-naphthyridin-2-one

Sources & evidence

ORD record
ord-45c7a5cda9354079bbed2fb9b3523a66
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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