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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1019883Generated: October 30, 2026

2-Chloro-7-methoxyquinoline → HCID 46852233, compound

https://huagongshe.com/reaction/1019883

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-7-methoxyquinolineHCID 12415558—
Reactant3-Oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]thiazine-6-carboxylic acidHCID 21873787—
Reactant[1-(2-Hydroxy-ethyl)-piperidin-4-yl]-carbamic acid tert-butyl esterHCID 45076484—
ProductHCID 46852233HCID 46852233—

Reaction Steps

The title compound is prepared as an off-white lyophilizated powder following Scheme 1 and in analogy to Examples 1 and 12 using 2-chloro-7-methoxy-quinoline, [1-(2-hydroxy-ethyl)-piperidin-4-yl]-carbamic acid tert-butyl ester and 3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]thiazine-6-carboxylic acid as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08716280B2
Source datasetuspto-grants-2014_05
ORD IDord-5b8a3fdc223044d5b33598d09cbbb34f
Source noteuspto-grants-2014_05