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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1019926Generated: October 31, 2026

3-Oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-6-carbaldehyde → HCID 46852849, compound

https://huagongshe.com/reaction/1019926

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-6-carbaldehydeHCID 21873737—
Reactant1-[2-(7-Methoxy-quinoxalin-2-ylsulfanyl)-ethyl]-piperidin-4-ylamineHCID 66746530—
ProductHCID 46852849HCID 46852849—

Reaction Steps

The title compound is prepared as a yellow solid (48 mg, 44% yield) following Scheme 3 and in analogy to Example 40 using 3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-6-carbaldehyde (40 mg, 0.22 mmol 1.0 eq) and 1-[2-(7-methoxy-quinoxalin-2-ylsulfanyl)-ethyl]-piperidin-4-ylamine (70 mg, 0.22 mmol, 1.0 eq) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08716280B2
Source datasetuspto-grants-2014_05
ORD IDord-838004c5134044f2a270bcedcb63b0b1
Source noteuspto-grants-2014_05