Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylic acid → 3-oxo-3,4-dihydro-2H-benzo[1,4]thiazine-6-carboxylic acid {1-[2-(7-methoxy-quinoxalin-2-ylsulfanyl)-3-morpholin-4-yl-propyl]-piperidin-4-yl}-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylic acid | HCID 760993 | — |
| 반응물 | 2-Chloro-7-methoxyquinoxaline | HCID 12686415 | — |
| 반응물 | [1-(2-Mercapto-3-morpholin-4-yl-propyl)-piperidin-4-yl]-carbamic acid tert-butyl ester | HCID 86662007 | — |
| 생성물 | 3-oxo-3,4-dihydro-2H-benzo[1,4]thiazine-6-carboxylic acid {1-[2-(7-methoxy-quinoxalin-2-ylsulfanyl)-3-morpholin-4-yl-propyl]-piperidin-4-yl}-amide | HCID 66746407 | — |
반응 단계
The title compound is prepared as a light brown lyophilizated powder following Scheme 3 and in analogy to Example 1 using 2-chloro-7-methoxy-quinoxaline, [1-(2-mercapto-3-morpholin-4-yl-propyl)-piperidin-4-yl]-carbamic acid tert-butyl ester and 3-oxo-3,4-dihydro-2H-benzo[1,4]thiazine-6-carboxylic acid as starting materials.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08716280B2 |
| 출처 데이터셋 | uspto-grants-2014_05 |
| ORD ID | ord-33443e5395c74e6aae6bd79d32fd3e2f |
| 출처 메모 | uspto-grants-2014_05 |