Triethylamine → HCID 49787468, compound

Participants

Reaction Steps

5-(2-chlorophenyl)-7-nitro-1,2,3,4-tetrahydroisoquinoline (0.065 g, 0.2 mmoles) was dissolved in anhydrous dimethylacetamide (1 ml) followed by the addition of triethylamine (0.068 mls) and butyryl chloride (0.0253 mls, 0.24 mmoles) followed finally by N,N-dimethylamino pyridine (catalytic amount). The reaction was left stirring at room temperature for 2.5 hours and the solution purified by automated C18 HPLC purification (0.0336 g, 47% yield, 100% pure, CO-AAW00017).

Provenance & Evidence