Phenylacetylene → HCID 57517076, compound

HRID 1020182Notes

Reaction equation

HRID 1020182 reaction equation
F[C:2]1[C:7]([F:8])=[CH:6][C:5](I)=[CH:4][N:3]=1.[CH3:10][C:11]1([CH2:15][OH:16])[CH2:14][O:13][CH2:12]1.[C:17]1([C:23]#[CH:24])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[F:8][C:7]1[C:2]([O:16][CH2:15][C:11]2([CH3:10])[CH2:14][O:13][CH2:12]2)=[N:3][CH:4]=[C:5]([C:24]#[C:23][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:6]=1

Participants

4

Reactant 3

HCID 10821PhenylacetyleneHCID 1378373-Methyl-3-oxetanemethanolHCID 113224272,3-Difluoro-5-iodopyridine

Product 1

HCID 57517076HCID 57517076, compound

Procedure

The title compound, yellow solid, MS: m/e=298.3 (M+H+), can be prepared in accordance with the general method of example 18 from 2,3-difluoro-5-iodopyridine, (3-methyloxetan-3-yl)methanol and phenylacetylene.

Sources & evidence

ORD record
ord-3b74a9fede2c4574927bc3f10b39a1e8
Source dataset
uspto-grants-2014_05
Patent number
US08716316B2

Reaction notes

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